Umphumela Wokuvikela weI-Skin MicroecologyEsikhumbeni
Izindlala ze-sebaceous zikhiqiza ama-lipids, agaywa ama-microorganisms ukuze enze ifilimu ye-lipid emulsified. Lawa mafilimu e-lipid aqukethe ama-fatty acids mahhala, aziwa nangokuthi amafilimu ane-asidi, anganciphisa izinto ze-alkaline ezingcoliswe esikhumbeni futhi avimbele amagciwane angaphandle (amagciwane adlulayo). , isikhunta namanye ama-microorganisms we-pathogenic akhula, ngakho-ke umsebenzi wokuqala we-flora yesikhumba evamile kuwumphumela obalulekile wokuvikela.
Ukuhlasela kwesikhumba nama-appendages, okuhlanganisa nezindlala zomjuluko (izindlala zomjuluko), izindlala ze-sebaceous, nezimbotshana zezinwele, zinezimbali zazo ezihlukile. Izindlala ze-sebaceous zixhuma izinhlayiya zezinwele ukuze zakhe iyunithi ye-follicular sebaceous, ekhiqiza i-lipid ecebile ebizwa ngokuthi i-sebum. I-Sebum iyifilimu yokuvikela i-hydrophobic evikela futhi igcobe isikhumba nezinwele futhi isebenza njengesihlangu esilwa namagciwane. Izindlala ze-sebaceous ziyi-hypoxic, zisekela ukukhula kwamabhaktheriya e-anaerobic asebenzayo njengeP. izinduna, equkethe i-P. acnes lipase eyehlisa isithunzi se-sebum, i-hydrolyzes triglycerides ku-sebum, futhi ikhiphe ama-fatty acids mahhala. Amagciwane angakwazi ukunamathela kulawa ma-fatty acids mahhala, asiza ukuchaza ukuhlanganiswa kwezindlala ze-sebaceous ngama-P. acnes, futhi lawa ma-fatty acids mahhala nawo afaka isandla ku-acidity ebusweni besikhumba (pH ka-5). Amagciwane amaningi avamile e-pathogenic, njenge-Staphylococcus aureus kanye ne-Streptococcus pyogenes, ayavinjelwa endaweni ene-asidi futhi ngaleyo ndlela alungele ukukhula kwe-coagulase-negative staphylococci kanye namagciwane e-coryneform. Nokho, ukuvaleka kwesikhumba kubangela ukwanda kwe-pH okuzovuna ukukhula kwe-S. aureus ne-S. pyogenes. Ngenxa yokuthi abantu bakhiqiza i-sebum triglycerides eningi kunezinye izilwane, ama-P. acnes amaningi agalela esikhumbeni somuntu.
Isikhathi sokuthumela: Jun-27-2022
