I-Hormone yehla ngobudala, kufaka phakathi i-estrogen, i-testosterone, dehydroshoepiandrosterone sulfate, kanye ne-hormone yokukhula. Imiphumela yama-hormone esikhunjeni yiminingi eminingi, kufaka phakathi okuqukethwe okwengeziwe kwe-collagen, ubukhulu besikhumba, kanye nokwenza ngcono i-hydration yesikhumba. Phakathi kwazo, ithonya le-estrogen lisobala kakhulu, kepha indlela yethonya layo kumaseli asemakethe ayiqondakali kahle. Umphumela we-estrogen esikhunjeni utholwa ikakhulukazi ngama-keratinocytes we-epidermis, ama-fibroblasts kanye nama-melanocytes we-dermis, kanye namangqamuzana ezinhlamvu zezinwele. Lapho ikhono labesifazane lokukhiqiza i-estrogen liyancipha, inqubo yokuguga kwesikhumba iyashesha. Ukushoda kwe-hormone estradiol kunciphisa umsebenzi wesendlalelo se-epidermis futhi kunciphisa ukuhlanganiswa kwemicu ye-collagen ne-elastic, konke okubalulekile ukuze kugcinwe ukuqina kwesikhumba okuhle. Ukwehla kwamazinga e-postmenopausausal at akuholela ekunciphiseni kokuqukethwe kwe-collagen yesikhumba, kepha futhi ne-metabolism yamaseli we-dermal ithinteka ngamazinga we-postmenopaul Ukuhlolwa kuqinisekisile ukuthi i-estrogen yabesifazane ye-toporical ingakhulisa ubukhulu, balondoloze ubukhulu besikhumba, futhi balondoloze umswakama wesikhumba kanye nomsebenzi wokubopha weStratum Corneum ngokwandisa i-glycosamincycans kanye ne-hyaluronic acid, ukuze isikhumba sihlalise amandla amahle. Kungabonakala ukuthi ukwehla komzimba we-Endocrine System Funct nakho kungenye yezinto ezibalulekile ezinethonya lendlela yokuguga kwesikhumba.
Ukuncishiswa kwemfihlo kusuka ku-pituitary, adrenal, kanye nama-gonads kunomthelela ezinguquko ezingokomfanekiso emzimbeni nasekuziphatheni kwamaphethini wokuziphatha ahambisana nokuguga. Amazinga we-Serum angu-17-estradiol, i-dehydroeepiandone, i-progesterone, i-hormone yokukhula, kanye ne-horsone yawo ye-insulin yokukhula ye-insulin (Igf) -Ngincipha ngeminyaka. Kodwa-ke, amazinga okukhula ama-hormone kanye ne-IGF-I esikhungweni sabesilisa wehla kakhulu, futhi ukwehla kwamazinga e-hormone kwezinye izindawo kungavela esigabeni esidala. Ama-Hormone angathinta ifomu lesikhumba kanye nomsebenzi, ukubhekelwa kwesikhumba, ukuphulukiswa, i-cortical lipogenesis, kanye ne-metabolism yesikhumba. Ukwelashwa kwe-Estrogen Replacement kungavimbela ukunqamuka kokuya esikhathini kanye nokuguga kwesikhumba okuphelele.
- "Isikhumba Epiphysiology" Yinmao Dong, Laji Ma, Imboni yamakhemikhali Press
Ngakho-ke, njengoba sikhula, ukunakwa kwethu kwezimo zesikhumba kufanele kukhule kancane kancane. Singasebenzisa abanye ochwephesheimishini yokuhlaziya isikhumbaUkubheka nokubikezela isigaba sesikhumba, qagela izinkinga zesikhumba kusenesikhathi, futhi ubhekane nazo ngenkuthalo.
Isikhathi sePosi: Jan-05-2023
