Ama-hormone ayancipha ngokuguga, okuhlanganisa i-estrogen, i-testosterone, i-dehydroepiandrosterone sulfate, kanye ne-growth hormone. Imiphumela yama-hormone esikhumbeni iphindaphindeka, okuhlanganisa okuqukethwe yi-collagen okwandisiwe, ukujiya kwesikhumba okwandisiwe, kanye nokuthuthukiswa komswakama wesikhumba. Phakathi kwazo, ithonya le-estrogen lisobala kakhulu, kodwa indlela esebenza ngayo ithonya layo emaseli ayisaqondakali kahle. Umphumela we-estrogen esikhumbeni ubonakala kakhulu ngama-keratinocyte e-epidermis, ama-fibroblast nama-melanocyte e-dermis, kanye namaseli e-hair follicle kanye nama-sebaceous glands. Lapho ikhono labesifazane lokukhiqiza i-estrogen lincipha, inqubo yokuguga kwesikhumba iyashesha. Ukuntuleka kwe-hormone i-estradiol kunciphisa umsebenzi wesendlalelo esiyisisekelo se-epidermis futhi kunciphisa ukwakheka kwe-collagen kanye nemicu e-elastic, konke okubalulekile ekugcineni ukuqina kwesikhumba okuhle. Ukwehla kwamazinga e-estrogen angemva kokunqamuka kokuya esikhathini akuholeli nje kuphela ekunciphiseni okuqukethwe yi-collagen yesikhumba, kodwa futhi nokuguqulwa kwamangqamuzana esikhumba kuthintwa amazinga e-estrogen aphansi angemva kokunqamuka kokuya esikhathini, futhi lezi zinguquko zingashintshwa ngokushesha ngokusetshenziswa kwe-estrogen endaweni engaphandle. Ukuhlolwa kuqinisekisile ukuthi i-estrogen yabesifazane esetshenziswayo ingandisa i-collagen, igcine ukujiya kwesikhumba, futhi igcine umswakama wesikhumba kanye nomsebenzi wokuvimbela we-stratum corneum ngokwandisa ama-glycosaminoglycans ane-acidic kanye ne-hyaluronic acid, ukuze isikhumba sigcine ukuqina okuhle. Kungabonakala ukuthi ukwehla komsebenzi wesistimu ye-endocrine yomzimba nakho kungenye yezinto ezibalulekile ezithonya indlela yokuguga kwesikhumba.
Ukuncipha kokukhishwa kwe-pituitary, adrenal, kanye ne-gonads kunegalelo ekushintsheni kwezimpawu emzimbeni nasesikhumbeni kanye namaphethini okuziphatha ahlobene nokuguga. Amazinga e-serum e-17β-estradiol, i-dehydroepiandrosterone, i-progesterone, i-growth hormone, kanye ne-hormone yabo engezansi ye-insulin growth factor (IGF)-I ayancipha ngokuguga. Kodwa-ke, amazinga e-growth hormone kanye ne-IGF-I ku-serum yabesilisa ancipha kakhulu, futhi ukwehla kwamazinga e-hormone kwezinye izakhamuzi kungenzeka esigabeni sobudala. Ama-hormone angathinta ukwakheka kwesikhumba kanye nokusebenza, ukungena kwesikhumba, ukuphulukiswa, i-cortical lipogenesis, kanye ne-metabolism yesikhumba. Ukwelashwa kokufaka esikhundleni se-estrogen kungavimbela ukunqamuka kokuya esikhathini kanye nokuguga kwesikhumba okungokwemvelo.
——”I-Skin Epiphysiology” Yinmao Dong, Laiji Ma, Chemical Industry Press
Ngakho-ke, njengoba sikhula, ukunaka kwethu izimo zesikhumba kufanele kukhule kancane kancane. Singasebenzisa ochwepheshe abangochwephesheimishini yokuhlaziya isikhumbaukuqaphela nokubikezela isigaba sesikhumba, ukubikezela izinkinga zesikhumba kusenesikhathi, nokubhekana nazo ngenkuthalo.
Isikhathi sokuthunyelwe: Jan-05-2023
