Amathiphu Okunakekelwa Kwesikhumba——Izici Ezithinta Ukuqina Kwesikhumba

I-elastin yomuntu ikhiqizwa ngokuyinhloko kusukela ku-embryonic sekwephuzile ukuya esikhathini sokuqala somntwana, futhi cishe ayikho i-elastin entsha ekhiqizwa phakathi nokukhula. Imicu ye-elastic iba nezinguquko ezihlukene ngesikhathi sokuguga okungapheli kanye ne-photoaging.

1. Ubulili nezitho ezahlukene zomzimba

Emuva ngo-1990, ezinye izazi zahlola amavolontiya angu-33 ukuze zihlole ukunwebeka kwesikhumba ezingxenyeni ezingu-11 zomzimba womuntu.

Kubonisa ukuthi ukunwebeka kwesikhumba kuhluke kakhulu phakathi kwezingxenye ezahlukene; kuyilapho ngokuyisisekelo ungekho umehluko obalulekile phakathi kobulili obuhlukene

Ukunwebeka kwesikhumba kancane kancane kuncipha ngokuya ngeminyaka.

2. Ubudala

Ngokukhula kweminyaka, isikhumba esigugayo asinwebekanga futhi sithambile kunesikhumba esincane, futhi inethiwekhi ye-elastic fiber iyaphuka futhi yehle, ibonakale njengokufiphala kwesikhumba kanye nemibimbi emihle; ekugugeni okungapheli, hhayi kuphela Ukuwohloka kwe-fibrous kwezingxenye ze-ECM, kodwa futhi nokulahlekelwa ezinye izingcezu ze-oligosaccharide. I-LTBP-2, LTBP-3, ne-LOXL-1 zonke zazilawulwa phezulu, futhi i-LTBP-2 ne-LOXL-1 idlala indima ebalulekile ekulawuleni nasekugcineni i-fibrin deposition, ukuhlanganisa, kanye nesakhiwo ngokubopha i-fibulin-5. Iziphazamiso ezihlobene ne-factor expression ivela njengezindlela zokwandisa ukuguga okungapheli.

3. Izici zemvelo

Ukulimala kwezici zemvelo esikhumbeni, ikakhulukazi ukuthwebula izithombe, ukungcoliswa komoya nezinye izici kuye kwanakwa kancane kancane, kodwa imiphumela yocwaningo ayihlelekile.

Isikhumba sokuthwebula isithombe sibonakala ngokulungiswa kabusha kwe-catabolic kanye ne-anabolic nokuguqulwa. Isikhumba sibonakala simahhadlahhadla futhi sishwabene ngokujulile ngenxa yokuthi akukona nje kuphela ukulahlekelwa ama-microfibril acebile nge-fibrillin lapho kuhlangana khona i-epidermis-dermal, ukuwohloka kwe-elastin, kodwa okubaluleke nakakhulu, ekufakweni kwezinto ezixubile ze-elastin ku-dermis ejulile, umsebenzi we-elastin othintekayo.

Ukulimala kwesakhiwo emicu enwebekayo yesikhumba akunakulungiseka ngaphambi kweminyaka eyi-18, futhi ukuvikelwa kwe-UV kubalulekile phakathi nesigaba sokukhula. Kungase kube nezinqubo ezimbili zokukhanya kwelanga okunwebekayo kwe-fiber: imicu enwebekayo yonakaliswa yi-elastase ekhishwa amangqamuzana azungezile noma ifakwe imisebe ye-UV, futhi imicu enwebekayo igobile phakathi nenqubo yokuhlanganisa; ama-fibroblasts anomphumela wokukhuthaza imicu enwebekayo ukuze kugcinwe umugqa. Umphumela uba buthaka, okuphumela ekugobeni.— Yinmou Dong Chemical Industry Press, 158-160

Inqubo yokushintsha ukunwebeka kwesikhumba ingase ingabonakali ngokwanele emehlweni enyama, futhi singasebenzisa uchwephesheisikhumba sokuxilonga analyzerbheka futhi ngisho nokubikezela umkhuba wokushintsha wesikhathi esizayo wesikhumba.

Ngokwesibonelo,ISEMECO or I-Resur Skin Analyzer, ngosizo lokukhanyisa okuqeqeshiwe kanye nekhamera enencazelo ephezulu yokufunda ulwazi lwesikhumba, kuhlanganiswe ne-algorithm yokuhlaziya i-AI, ingakwazi ukubona imininingwane nokubikezela kwezinguquko zesikhumba .