Amathiphu Okunakekela Isikhumba——Izici Ezithinta Ukunwebeka Kwesikhumba

I-elastin yomuntu ikhiqizwa kakhulu kusukela ekupheleni kombungu kuya ekuqaleni kokuzalwa, futhi cishe ayikho i-elastin entsha ekhiqizwa ngesikhathi sobudala. Imicu enwebekayo idlula ezinguqukweni ezahlukene ngesikhathi sokuguga okungokwemvelo kanye nokuguga nge-photoaging.

1. Ubulili kanye nezingxenye zomzimba ezahlukene

Kusukela ngo-1990, ezinye izazi zahlola izisebenzi zokuzithandela ezingu-33 ukuze zifunde ukuqina kwesikhumba ezingxenyeni ezingu-11 zomzimba womuntu.

Kubonisa ukuthi ukuqina kwesikhumba kuhluke kakhulu phakathi kwezingxenye ezahlukene; kuyilapho empeleni kungekho mehluko omkhulu phakathi kobulili obuhlukene

Ukuqina kwesikhumba kwehla kancane kancane njengoba iminyaka ikhula.

2. Ubudala

Njengoba ukhula, isikhumba sokuguga esingokwemvelo asiguquki futhi asiguquki kakhulu kunesikhumba esincane, futhi inethiwekhi ye-fiber elastic iyaphuka futhi yehle, okubonakala njengokuthamba kwesikhumba kanye nemibimbi emincane; ekugugeni okungokwemvelo, hhayi nje kuphela ukuwohloka kwe-fibrous kwezingxenye ze-ECM, kodwa futhi nokulahlekelwa ezinye izingcezu ze-oligosaccharide. I-LTBP-2, i-LTBP-3, kanye ne-LOXL-1 zonke zalungiswa, kanti i-LTBP-2 kanye ne-LOXL-1 zidlala indima ebalulekile ekulawuleni nasekulondolozeni ukufakwa kwe-fibrin, ukuhlanganiswa, kanye nesakhiwo ngokubopha i-fibulin-5. Ukuphazamiseka okuhlobene nokubonakaliswa kwezinto kuvela njengezindlela zokwandisa ukuguga okungokwemvelo.

3. Izici zemvelo

Umonakalo wezinto zemvelo esikhumbeni, ikakhulukazi ukuthwebula izithombe, ukungcola komoya nezinye izinto kuye kwanakwa kancane kancane, kodwa imiphumela yocwaningo ayihlelekile.

Isikhumba esishintsha umbala sibonakala ngokuguqulwa kwe-catabolic kanye ne-anabolic kanye nokuguqulwa. Isikhumba sibonakala simahhadlahhadla futhi sishwabene ngokujulile hhayi nje ngenxa yokulahlekelwa ama-microfibrils acebile nge-fibrillin ekuxhumaneni kwe-epidermis-dermal, ukuwohloka kwe-elastin, kodwa okubaluleke kakhulu, ukubekwa kwezinto ezingasebenzi kahle ze-elastin e-dermis ejulile, umsebenzi we-elastin othintekile.

Umonakalo wesakhiwo semicu yesikhumba enwebekayo awunakuguqulwa ngaphambi kokuba uneminyaka engu-18, futhi ukuvikelwa kwe-UV kubalulekile ngesikhathi sokukhula. Kungase kube nezindlela ezimbili zokukhanya kwelanga kwe-fiber enwebekayo: imicu ye-elastic yonakaliswa yi-elastase ekhishwa amaseli azungezile noma ikhanyiswe yi-UV, kanti imicu ye-elastic iyagoba ngesikhathi senqubo yokwenziwa; ama-fibroblast anomphumela wokukhuthaza imicu ye-elastic ukuze igcine ukulingana. Umphumela uba buthakathaka, okuholela ekugobeni.—— Yinmou Dong I-Chemical Industry Press, 158-160

Inqubo yokushintsha kokuqina kwesikhumba ingase ingabonakali ngokwanele emehlweni, futhi singasebenzisa ochwephesheisihlaziyi sokuxilonga isikhumbaqaphela futhi ubikezele ngisho nokushintsha kwesikhumba esikhathini esizayo.

Ngokwesibonelo,I-ISEMECO or Isihlaziyi Sesikhumba Esivuselelayo, ngosizo lokukhanya kobungcweti kanye nekhamera ecacile yokufunda ulwazi lwesikhumba, kuhlanganiswe ne-algorithm yokuhlaziya i-AI, ingabona imininingwane kanye nokubikezela izinguquko zesikhumba.