Indlela ye-squalene oxidation ilele ekutheni isikhathi sayo esiphansi se-ionization singanikela noma samukele ama-electron ngaphandle kokulimaza ukwakheka kwamangqamuzana, futhi i-squalene inganqamula ukusabela kweketango lama-hydroperoxides kumzila we-lipid peroxidation. Ucwaningo luye lwabonisa ukuthi i-peroxidation ye-sebum ibangelwa ikakhulukazi umoya-mpilo we-singlet, futhi izinga lokucisha umoya-mpilo le-singlett elingaguquki le-squalene ku-sebum yomuntu likhulu kakhulu kunamanye ama-lipids esikhumbeni somuntu. ukushabalala njalo. Kodwa-ke, kufanele kuqashelwe ukuthi nakuba i-squalene ingavimbela i-lipid peroxidation, imikhiqizo ye-squalene, efana ne-unsaturated fatty acids, nayo inomphumela ocasulayo esikhumbeni.
I-squalene peroxide ingase ibambe iqhaza elikhulu ku-pathogenesis ye-acne. Kumamodeli okuhlola izilwane, kuye kwatholakala ukuthi i-squalene monoperoxide i-comedogenic kakhulu, futhi okuqukethwe kwe-squalene peroxide kancane kancane kuyanda ngaphansi kwemisebe ye-UV. Ngakho-ke, kuphakanyiswa ukuthi iziguli zezinduna kufanele zinake ukuvikelwa kwelanga, futhi ama-sunscreens angagwema i-squalene peroxidation ekugxilweni komzimba okubangelwa imisebe ye-ultraviolet.
Umhlaziyi wesikhumbaingasetshenziswa ukuthola umphumela we-sun cream. Isithombe se-UV siboniswa luhlaza okwesibhakabhaka okumnyama uma kufakwa isithako sokuvikela elangeni samakhemikhali; uma kusetshenziswa isikrini sokuzivikela elangeni esingokoqobo, isithombe siyakhanya, sifana nezinsalela ze-fluorescent.
Isikhathi sokuthumela: Apr-29-2022