Indlela yocingo e-squalene oxidation ilele lapho isikhathi sayo esiphansi se-ionizer Ucwaningo luye lwabonisa ukuthi i-peronidation ye-sebum idalwa kakhulu yi-wenglet oxygen, futhi i-oksinglegen oxygen eqeda izinga eliguqukayo njalo e-squalene e-sebum yomuntu likhulu kakhulu kunalelo lamanye ama-lipid esikhunjeni somuntu. extinction constant. Kodwa-ke, kufanele kuqashelwe ukuthi yize i-squalene ingavimba i-perloxidation ye-lipid, imikhiqizo ye-squalene, njengama-acid angenakugcotshwa, futhi inomphumela ocasulayo esikhunjeni.
Squalene peroxide may play a major role in the pathogenesis of acne. Kumamodeli wokuhlola izilwane, sekusunguliwe ukuthi i-squalene monoperoxide ihlehlise kakhulu, futhi okuqukethwe kwe-squalene peroxide kukhuphuka kancane kancane ngaphansi kwe-UV irradiation. Ngakho-ke, kuphakanyiswa ukuthi iziguli ze-Acne kufanele zinake ukuvikela ilanga, futhi ama-sunscreens angagwema ukufakwa kwe-squalene ekugxilweni komzimba okubangelwa imisebe ye-ultraviolet.