Indlela yokusebenza kwe-squalene oxidation itholakala ngokuthi isikhathi sayo esiphansi se-ionization singanikela noma samukele ama-electron ngaphandle kokulimaza isakhiwo sama-molecule samaseli, kanti i-squalene ingaqeda ukusabela kwe-chain ye-hydroperoxides endleleni ye-lipid peroxidation. Izifundo zibonise ukuthi i-peroxidation ye-sebum ibangelwa kakhulu yi-singlet oxygen, kanti i-singlet oxygen quenching rate constant ye-squalene ku-human sebum inkulu kakhulu kuneyamanye ama-lipid esikhumbeni somuntu. Kodwa-ke, kufanele kuqashelwe ukuthi yize i-squalene ingavimba i-lipid peroxidation, imikhiqizo ye-squalene, njenge-unsaturated fatty acids, nayo inomphumela ocasulayo esikhumbeni.
I-squalene peroxide ingadlala indima enkulu ekubangeleni i-acne. Emamodelini okuhlola ezilwaneni, kuye kwatholakala ukuthi i-squalene monoperoxide ibangela i-comedogenic kakhulu, futhi okuqukethwe yi-squalene peroxide kuyanda kancane kancane ngaphansi kokukhanya kwe-UV. Ngakho-ke, kuphakanyiswa ukuthi iziguli ze-acne kufanele zinake ukuvikelwa elangeni, futhi ama-sunscreen angagwema i-squalene peroxidation ekugxilweni komzimba okubangelwa imisebe ye-ultraviolet.
Isihlaziyi sesikhumbaingasetshenziswa ukuthola umphumela wokhilimu welanga. Isithombe se-UV sikhonjiswa okwesibhakabhaka obumnyama uma kusetshenziswa i-sunscreen yamakhemikhali; uma kusetshenziswa i-sunscreen ebonakalayo, isithombe siyakhanya, sifana nezinsalela ze-fluorescent.
Isikhathi sokuthunyelwe: Ephreli-29-2022
