Izici ezintathu zesikhumba sokuguga

Isici sokuqala sokuguga kwesikhumba:

Imisebe ye-UV, Photoling

I-70% yokuguga kwesikhumba ivela ekutholeni izithombe

Imisebe ye-UV ithinta i-collagen emzimbeni wethu, okugcina isikhumba sibukeka sincane. Uma i-collagen incipha, isikhumba sizokwehlisela ukunwebeka, ukugcotshwa, ubumba, ubumba, ithoni yesikhumba engalingani, i-hyperpigmentation, i-pigmentation kanye nezinye izinkinga zesikhumba.

I-Sun's Broad Spectrum ihlukaniswe i-UVA ne-UVB. Imisebe ye-UVB inama-wavelength amafushane futhi ingashisa ungqimba oluphezulu lwesikhumba sethu, esingakwazi ukungena ekujuleni kwesikhumba; Kodwa-ke, imisebe ye-UVA inama-wavelength amade futhi ingangena esikhunjeni futhi ijule esikhunjeni, ekugcineni ibe buthaka i-collagen futhi iholele ekuthuthukisweni kwemibimbi.

Ngamagama alula, i-UVA iholela ekugugeni, i-UVB kuholela ekuvuleni, futhi ukukhanya kwe-ultraviolet kungalimaza i-Cellular, futhi ukuhlanganiswa kwe-FIBROBLAST, okuholela ekuguqukeni kwamaselula, ukuguga kanye ne-apoptosis. Ngakho-ke, i-UV ikuyo yonke indawo, noma ngabe ilanga noma inamafu, kudingeka wenze umsebenzi omuhle wokuvikelwa kwelanga.

Isici sesibili esibaluleke kakhulu ekugugeni kwesikhumba

Ama-radicals wamahhala we-oxidative

Igama eliyisihluthulelo lama-radicals wamahhala 'oxygen'. Siphefumula cishe amaphesenti angama-98 kuye kwangama-99 omoya-mpilo ngaso sonke isikhathi lapho siphefumula; Kusetshenziselwa ukushisa ukudla esikudlayo nokukhipha ama-molecule amancane amaseli ethu ku-metabolise, futhi kukhipha amandla amaningi okwenza izicubu zethu zisebenze.

Kepha mhlawumbe u-1% noma u-2% we-oksijini ukhetha indlela ehlukile neyingozi, le mali encane ye-oksijini, evame ukubizwa ngama-radicals wamahhala, ahlasela amaseli ethu. Ngokuhamba kwesikhathi, lo monakalo uyanqwabelana ngokuhamba kwesikhathi.

Okuphawuleka kakhulu yizimpawu zokuguga ezivela esikhunjeni. Umzimba wethu unendlela yokuvikela elungisa umonakalo owenziwe kumaseli ethu ngama-radicals wamahhala, kepha lapho ama-radicals yamahhala aqongelela ngokushesha ukwedlula amaseli omzimba angawalungisa, kancane kancane isikhumba.

Lesi sithombe esingenhla siyisicubu sangempela sesikhumba somzimba wethu, ungabona ngokusobala ukuthi i-epidermis ephezulu inobumnyama futhi ama-dermis aphansi aqhakaza kancane, amaseli akhiqiza lapho sikhiqiza khona ama-fibroblasts, okuyimishini yokwenza ama-collagen.

Ama-fibroblasts phakathi nesithombe angama-fibroblasts, futhi i-spider web ebazungezile i-collagen. I-Collagen ikhiqizwa yi-fibroblasts, kanti isikhumba esincane siyi-collagen network enobukhulu obuthathu futhi ngokuqinile, nge-fibroblasts edonsa ngamandla emicu ye-collagen ukunikeza isikhumba esincane ukugcwala okugcwele.

Futhi isikhumba esidala, i-fibroblasts kanye nokuxhumeka kwe-collagen phakathi kokuhlakazeka kwama-fibroblasts agugile kuzokwenqaba ukungena kwe-collagen, ngokuhamba kwesikhathi, lesi sikhumba saqala ukumiswa kokuguga kwesikhumba, sikuxazulula kanjani i-oximation yesikhumba etholakele?

Ngaphezu kokunaka kakhulu i-sunscreen, singasebenzisa amanye ngamavithamini a, Vitamin E, Reveratrol kanye nezinye izithako zemikhiqizo yokunakekelwa kwesikhumba; Imvamisa futhi kungadla izithelo nemifino egqamile ngokwengeziwe, njengotamatisi, utamatisi ucebile eLicCopene.

Kungadonsa kahle umoya-mpilo futhi uvikele ukucindezelwa kwe-oxidative, ungadla futhi i-broccoli eyengeziwe, i-broccoli iqukethe ingxenye ebizwa nge-mustard Amafutha glycosides, ngemuva kokuthatha izithako, ukuze izitokisi zesikhumba zikwazi ukuthuthukisa ukumelana kwamaseli kokuguga.

Isici sesithathu esibaluleke kakhulu ekugugeni kwesikhumba

Isikhumba Glycation

I-Glycation, ngamagama ochwepheshe, ibizwa ngokuthi ukusabela kwe-glycosyltation okungeyona eye-enzymatic noma ukusabela kukamayela. Umgomo ukuthi ukunciphisa ushukela ubopha amaprotheni uma kungekho ama-enzyme; Ukunciphisa ushukela kuguqulwa kakhulu ngamaprotheni, futhi kunciphisa ushukela kanye namaprotheni athola i-oxidation ende, ama-dehydrogenation, kanye nokusabela kabusha, okuholela ekukhiqizweni kwemikhiqizo ye-glycosylation yokugcina sekwephuzile.

Iminyaka yeqembu elingenakuphikiswa, eliphuzi, elinemibukiso yemvelo enobuntu, ehambisana nalokhu ongeyesabi ukubhujiswa kwe-enzyme, futhi kungenye yezinkampani eziphambili zokuguga kwabantu. Njengoba sikhula, ubudala buqongelela emzimbeni, okuholele ekukhuphukeni kobulukhuni bezindonga zangaphakathi zemithambo yegazi, nokubhujiswa kwe-glycaged okubangelwa amaprotheni anempilo futhi kuguqula amaprotheni anempilo asebekhulile Izakhiwo zamaphrotheni, eziholela ekugugeni nasekulahlekelweni kwe-elasticity of Collagen kanye ne-elastic fibers ku-dermis.